Your doctor or pharmacist can help you choose one that doesnt have extra ingredients that you dont need. upper respiratory tract infection, including the common cold. For more information and to find out if youre eligible for support, call 800-727-5400 or visit the program website. MNT is the registered trade mark of Healthline Media. Taking Zetia with a statin may cause this side effect. These conditions can raise your risk of muscle problems while taking Zetia. The symptoms develop immediately and include dizziness and an intense headache. Zetia may not be right for you if you have certain medical conditions or other factors affecting your health. This active drug is also available as a generic medication. If left untreated, it can cause your kidneys to stop working properly. Lipitor is part of the statin drug class. Phase IV trials are used to detect adverse drug . They may have a preference for one version or the other. Postural orthostatic tachycardia syndrome (POTS) or chronic orthostatic intolerance (OI) is classified as an autonomic dysfunction of the nervous system from an abnormal vasovagal response.. Theyll work with you to create a treatment plan based on scientific evidence and your unique health history. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. Statins are another type of medication used to lower cholesterol. Learn about the side effects it can cause and how to manage them. Lipitor is also FDA-approved for the following conditions when used with a low-cholesterol diet: primary dysbetalipoproteinemia in adults (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), liver complications, such as high levels of, Both Zetia and Crestor are FDA-approved to treat the following conditions* when used with a. Crestor is also FDA-approved for the following conditions in adults when used with a low-cholesterol diet: primary dysbetalipoproteinemia (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), pain on the right side of your body, below your ribs, in adults as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin drug), in adults in combination with a fenofibrate, in combination with statins, in people with hepatic disease, in combination with statins, in people with elevated hepatic transaminases, in combination with statins, during pregnancy or in someone planning to become pregnant, in combination with statins, while breastfeeding, in people who have a known allergy to Zetia. Learn about side effects, dosage, and more. For more information about taking Zetia during pregnancy, see the Zetia and pregnancy section above. Nearly two years passed before Bock received an official diagnosis: postural orthostatic tachycardia syndrome, or POTS. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. For treatment of mixed hyperlipidemia, Zetia is indicated to reduce total cholesterol, LDL cholesterol, non-HDL cholesterol, and ApoB. POTS is commonly associated with low levels of fluid. For primary high cholesterol, Zetia is FDA-approved for use in adults and children* to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet. Cholesterol itself isnt a harmful substance. Symptoms of a swollen gallbladder may include: Tell your doctor if you experience gallstones while using Zetia with fenofibrate. I am a stay at home mama to a sweet baby girl, and wife to an amazing h. (Fenofibrate is a drug used to lower your triglyceride levels.). In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. If youre taking Zetia alone, you shouldnt need to take CoQ10. Some people with POTS also may have one or more . Do not use more Zetia than your doctor recommends. These symptoms can be signs of an infection. What is considered high cholesterol? Zetia isnt known to interact with grapefruit or any other foods. (A class of medications is a group of drugs that work in a similar way.) . Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. A decrease in the transport of intestinal cholesterol to the liver reduces stores of hepatic cholesterol. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. If you miss a dose of Zetia, you can take your missed dose as soon as you remember. Lipitor contains the active drug atorvastatin. Learn more about how grapefruit may interact with medications. Postural Orthostatic Tachycardia Syndrome (POTS) is a blood flow disorder that causes a sudden spike in heartbeat with no change in blood pressure when going from a horizontal or seated to a standing position. People with this condition have high levels of plant sterols. (A class of drugs is a group of medications that work in a similar way.) Some people may develop mild or serious side effects during Zetia treatment. But in studies, some people had to stop taking the drug due to feeling dizzy. Zetia has a well-documented safety profile. To determine whether you have high cholesterol, your doctor will do a blood test called a lipid panel. Zetia is sometimes used with medications in the statin drug class. Both Zetia and Lipitor come as tablets that are swallowed. Youll likely take Zetia once a day. Blood pressure medications and water pills (diuretics) All blood pressure medications can cause ED, but thiazide diuretics and beta blockers are the most likely to do so. Zetia may also increase the amount of cholesterol thats stored in your gallbladder. Talk with your doctor if you have questions about managing your blood pressure or blood sugar while using Zetia. For this purpose, Zetia may be used: The only FDA-approved dosage of Zetia is 10 mg once a day. Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. Many rare diseases have limited information. Legal news and analysis on health care, hospitals, insurers, medical suppliers. You can also ask your pharmacist for information on how to dispose of your medication. Ezetimibe may cause side effects. This is not a complete list of side effects and others may occur. The list below includes factors to consider. Started Zetia 10mg and within a few hours horrible stomach pains began as well as constant flatulence. Zetia is sometimes used with medications in the statin drug class. If you have a history of heavy alcohol use and are taking Zetia with a statin drug, you may have a higher risk of side effects. If you develop serious side effects while taking Zetia, call your doctor right away. This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. . Tried Zetia again to rule out diet causing stomach issues but got same result. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Zetias mechanism of action is considered complementary to that of statins and fenofibrate. But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. Also, tell your doctor right away if you become pregnant while taking this drug. Sharing this information can help you avoid potential interactions. For more information, see the How Zetia works section below. The side effects from Zetia .. muscle weakness, joint pain, upper respiratory infectikns resemble the symptoms of malabsorption of Vitamin A,D, E and K. Our bodies need cholestorol to help coat our nerves and help with brain function and it naturally increases as we get older, so why are we trying to lower it, could this be why we are . Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. How long a medication remains good can depend on many factors, including how and where you store the medication. Ezetimibe can cause the breakdown of muscle tissue . Yes, there are a few. Before taking Zetia, talk with your doctor about your health history. They may be able to help determine whats causing your hair loss. Zetia is also available in a generic form called ezetimibe. This causes less cholesterol to travel from your small intestine to your liver. In the studies: Zetia is approved to treat the following conditions in children ages 10 years and older when used with a low-cholesterol diet: To learn more about how Zetia is used for these conditions, see the sections above. Temporary excursions of 59F to 86F (15C to 30C) are allowed. Talk with your doctor about any liver problems you may have and whether its safe for you to take Zetia. Cholesterol absorption inhibitors prevent your small intestine from absorbing cholesterol. Zetia generally costs less than Lipitor. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. The manufacturer of Zetia hasnt stated whether the tablets can be crushed, split, or chewed. In studies, weight changes didnt occur in people who took the drug. You should also look for supplements from reputable manufacturers. They may suggest foods that can help lower your cholesterol and reduce your risk of weight gain. Short term Zetia side effects include mild fatigue, dizziness, diarrhea, nausea and headache. This can cause Zetia to be less effective. Zetia belongs to a class of drugs called cholesterol absorption inhibitors. For more information, see the Precautions section below. They may also check you for signs of muscle breakdown or kidney damage. Lipitor ( atorvastatin) and Zetia ( ezetimibe) are used to lower cholesterol levels in the blood. Diarrhea is a common side effect of Zetia. Merck, the manufacturer of Zetia, offers a Patient Assistance Program. Its a place where people with certain conditions can find support and connect with others. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Total cholesterol levels were reduced by an average of: LDL (bad) cholesterol levels were reduced by an average of: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Its also not known if the drug is safe to take while breastfeeding or whether the drug passes into breast milk. They can tell you whether the supplement may interact with any medications youre taking. Qu H, et al. The side effects of Zetia in children are similar to the side effects in adults. Or should I wait to see if I develop such side effects? (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). Zetia can cause certain side effects, some of which are more common than others. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. Brain fog. If you need to take these drugs together, take Zetia at least 2 hours before or 4 hours after taking cholestyramine. And taking it with Zetia and a statin likely wont cause any problems. Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. The children took Zetia and simvastatin or simvastatin alone. Zetia is a prescription drug used to treat certain types of high cholesterol. If you become pregnant while taking Zetia alone or with a statin drug, tell your doctor about your pregnancy right away. * Sex and gender exist on spectrums. Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. See the Mild side effects and Serious side effects sections above for more information. Statin drugs arent safe to use during pregnancy. If the side effects seem life threatening or if you think youre having a medical emergency, immediately call 911 or your local emergency number. Learn about alternatives like new drugs, A new class of self-injectable medications are showing promise in treating high cholesterol. Tell them about all prescription, over-the-counter, and other drugs you take. The insurance company will review the prior authorization request and decide if the drug will be covered. This can increase your risk of side effects from either medication. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. If you and your doctor decide that Zetia treatment isnt right for you, you simply wont take any more doses. Its not known if Zetia is safe to take during pregnancy. Get answers to some frequently asked questions about Zetias side effects. Zetia isnt a statin drug. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). For instance, some interactions can interfere with how well a drug works. Recently, POTS has been diagnosed in some people who have had COVID-19. Its not known if Zetia is safe to take during pregnancy. The heartbeat increases with a feeling of the heart fluttering. This in turn increases clearance of cholesterol from the blood. A generic drug is an exact copy of the active drug in a brand-name medication. Theyll likely have you stop taking Zetia and any statin drug you may be using. We talked to experts about, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Both drugs are typically taken once each day. If you have questions about the differences between Zetia and statin drugs, talk with your doctor. tightness of chest or wheezing. More research is needed to know for sure. It only comes in a strength of 10 milligrams (mg). Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by lightheadedness or dizziness when standing and a racing heart. Zetia is meant to be used in combination with a diet thats low in saturated fat and cholesterol. Ezetimibe (the active drug in Zetia) is also available in a combination drug that contains simvastatin. Zetia comes as a tablet that you swallow. And do not stop using Zetia unless your doctor recommends it. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Lipitor, or with both drugs (when taken individually). If you use Zetia and warfarin together, your doctor may want to monitor you more closely during your treatment. POTS is an unusual condition in which your heart rate speeds up by 30 or more beats per minute with little or no change in blood pressure. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. However, 0.3% of people who took Zetia alone experienced joint pain so bothersome that they had to stop treatment. They can suggest ways to help relieve your side effects, or they may recommend a different treatment option for you. In clinical studies that lasted an average of 12 weeks, Zetia was compared with a placebo (a treatment with no active drug). POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. A medication timer may be useful, too. Less commonly, taking Zetia may lead to serious side effects. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Crestor, or with both drugs (when taken individually). You can take Zetia with or without food. Zetia can cause the breakdown of muscle tissue, which can lead to kidney failure. stuffy nose. However, 0.5% of adults and children who took Zetia with a statin drug experienced muscle pain so bothersome that they had to stop treatment. The effect of Zetia, atorvastatin, or simvastatin on other types of cholesterol levels in this study isnt known. If you feel dizzy from Zetia, it may help to take your dose at bedtime. Here we look at how Zetia and Lipitor are alike and different. Variable: Generally it is well tolerated but common side effects include:muscle aches , abdominal discomfort / diarrhea, fatigue. Talk with your doctor about the risks of taking Zetia with warfarin. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. This is because every persons body responds differently to medications. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. Statins are drugs used to lower cholesterol. In studies, some people had to stop taking Zetia because of this side effect. They didnt take Zetia with other drugs that also treat high cholesterol. The generic form of Zetia costs about the same as the generic form of Crestor. So stopping Zetia may lead to an increase in your cholesterol levels. Our website services, content, and products are for informational purposes only. Theyll guide you on the safest treatment options for you. They may have suggestions depending on your weight and health goals. Mild side effects of Zetia when taken with a statin (another kind of cholesterol -lowering drug) may include: infection, such as a respiratory . Risk factors for muscle-related problems. Examples of statin drugs include: Learn more about how grapefruit may interact with medications. Specific statins that were studied included atorvastatin (Lipitor), simvastatin (Zocor), pravastatin (Pravachol), and lovastatin. The Food and Drug Administration (FDA) approves prescription drugs such as Zetia to treat certain conditions. Clinical studies involved adults and children ages 10 years and older. Talk with your doctor to learn more about which medications are right for you. Your doctor will determine the best dosage to fit your needs. These side effects may include diarrhea, muscle or joint aches, and cold symptoms, such as sore throat and congestion. There arent any herbs or supplements that have been specifically reported to interact with Zetia. Zetia is a brand-name drug that contains the active drug ezetimibe. High cholesterol can raise your risk of heart disease. This list contains examples of serious side effects that can occur with both Zetia and Crestor (when taken individually). Zetia is primarily cleared from the body through fecal excretion. If your muscle-related side effects dont go away or become severe, tell your doctor right away. And generics tend to cost less than brand-name drugs. Another is trouble standing up, primarily because not enough blood returns to the heart upon standing, which causes a rapid increase in heart rate called tachycardia. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. If you would like to report to the FDA a side effect youve had with Zetia, you can do so through MedWatch. For more information about the effectiveness of Zetia for lowering your triglycerides, see the Zetia uses section above. Lying down on the bed, and raising your legs. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Your doctor will also prescribe a low-cholesterol diet for you to follow while taking Zetia. Your side effect notes can include things such as: Keeping notes and sharing them with your doctor will help your doctor learn more about how Zetia affects you. Talk with your doctor right away if you have fever or chills with your joint pain. Talk with your doctor or pharmacist if you have trouble swallowing Zetia tablets. In clinical studies of Zetia used with statin drugs to treat primary hyperlipidemia in adults and in children ages 10 years and older: It isnt known how long adults and children experienced muscle pain while taking Zetia with statin drugs in these clinical studies. And older it has approved standing and a racing heart about side effects safe for you if you fever! You may be used in combination with a low cholesterol/low fat diet and exercise to help determine whats causing hair... Dosage of Zetia hasnt stated whether the supplement may interact with any medications youre taking statin..., your doctor or pharmacist if you need to take these drugs together, your doctor right if... ( 15C to 30C ) are used to lower cholesterol the specific conditions Zetia can treat, the! Doctor decide that Zetia treatment POTS has been diagnosed in some people had stop. 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